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NMR Spectrometer: 600 MHz NB Varian Inova - Cryoprobe

Quick Specs

  • 600-MHz frequency
  • Equipped for protein structure determination and metabolomics

The Varian Inova 600-MHz nuclear magnetic resonance (NMR) spectrometer is a narrow-bore system equipped with a Varian Inova console. EMSL researchers primarily use this system to perform solution-state NMR experiments such as protein structure determinations, and metabolomic studies are also being performed.

The console is equipped with four radio frequency channels and a Z-axis gradient amplifier. The system is also outfitted with two solution probes: a 5-mm HCN (Z-gradient) probe and 5-mm HX (Z-gradient) probe. The console is controlled by a Sun Ultra 10 computer connected to the network.

Researchers may operate this system independently and are provided as much training as necessary for independent operation. Many users opt to operate this system remotely; in this case, the sample is shipped by the user to EMSL, where a facility researcher places the sample in the magnet and tunes the probe. The user then can operate the spectrometer through a secure connection over the Internet.

  1. Adsorption of Amelogenin onto Self-Assembled and Fluoroapatite Surfaces.
  2. αB-Crystallin: A Hybrid Solid-State/Solution-State NMR Investigation Reveals Structural Aspects of the Heterogeneous Oligomer.
  3. Structure of an Acetyl-CoA Binding Protein from Staphylococcus aureus Representing a Novel Subfamily of GCN5-related N-Acetyltransferase-like Proteins.
  4. Metabolomics in Lung Inflammation: A High Resolution ¹H NMR Study of Mice Exposed to Silica Dust .
  5. Structural Studies of the SET Domain from RIZ1 Tumor Suppressor.