Computational Biology: The Virtual Microbial Cell Simulator Text Box: Applications: Bioremediation of heavy metal, radioactive waste for environmental cleanup. Bioterrorism related to the inhalation of aerosolized microbes. Capability: Image process based on electron tomography, confocal microscopy, and NMR. Incorporates multiple spatial scales from single cells through communities. Flux based, genome-scale metabolic pathway descriptions of the production and use of energy within and between cells. Algorithms: Finite volume spatial integration coupled to Global Flux Balance for transport. Unstructured boundary-fitted / volume-filling meshes. Reaction/Diffusion transport models. High-performance, parallel implementation. Scalable from laptops to super-clusters. P3D Codes: DDV, OSO, NWGrid, NWPhys, GMV Authors: Harold Trease, TSTT Group Data Sources: Electron microscopy/tomography P3DText Box:

Home      << Previous       Next >>