Skip to main content

Kisurb Choe
Postdoctoral Research Associate

Kisurb Choe is a postdoctoral research associate investigating the spatial lipidomics involved with human health. He applies matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) with bioinformatics algorithms to develop laser ablation electrospray ionization sources. He participates in the Kidney Precision Medicine Project and the Human BioMolecular Atlas Program, applying  these approaches to investigate the spatial lipidomics and metabolomics in tissue samples for disease phenotyping. 

Research Interests

  • MALDI MS imaging  
  • High-throughput screen  
  • Instrumentation   

Education

  • PhD in biochemistry, University of Illinois Urbana-Champaign, 2022 
  • MS in biomanufacturing, North Carolina State University, 2017 
  • BA in biological sciences, Rice University, 2010 

Affiliations and Professional Service

  • Laboratory Assistant, Novozymes Biologicals, 2014  
  • Life Sciences Research Associate, Stanford University, 2011 – 2012  

Publications

2023 

  • Choe, Kisurb, and Jonathan V. Sweedler. “Workflow for High-Throughput Screening of Enzyme Mutant Libraries Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Analysis of Escherichia Coli Colonies.” Bio-Protocol 13, no. 21: e4862. https://doi.org/10.21769/BioProtoc.4862. 
  • Choe, Kisurb, Michael A. Jindra, Susan C. Hubbard, Brian F. Pfleger, and Jonathan V. Sweedler. “MALDI-MS Screening of Microbial Colonies with Isomer Resolution to Select Fatty Acid Desaturase Variants.” Analytical Biochemistry 672: 115169. https://doi.org/10.1016/j.ab.2023.115169. 
  • Jindra, Michael A., Kisurb Choe, Ratul Chowdhury, Ryan Kong, Soodabeh Ghaffari, Jonathan V. Sweedler, and Brian F. Pfleger. “Evaluation of Strategies to Narrow the Product Chain-Length Distribution of Microbially Synthesized Free Fatty Acids.” Metabolic Engineering 77: 21–31. https://doi.org/10.1016/j.ymben.2023.02.012. 

2021  

  • Choe, Kisurb, Pu Xue, Huimin Zhao, and Jonathan V. Sweedler. “MacroMS: Image-Guided Analysis of Random Objects by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.” Journal of the American Society for Mass Spectrometry 32, no. 5: 1180–88. https://doi.org/10.1021/jasms.1c00013.